听力与言语-语言病理学

行为科学

医学伦理学

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  • Ultrathin rhodium nanosheets.

    abstract::Despite significant advances in the fabrication and applications of graphene-like materials, it remains a challenge to prepare single-layered metallic materials, which have great potential applications in physics, chemistry and material science. Here we report the fabrication of poly(vinylpyrrolidone)-supported single...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4093

    authors: Duan H,Yan N,Yu R,Chang CR,Zhou G,Hu HS,Rong H,Niu Z,Mao J,Asakura H,Tanaka T,Dyson PJ,Li J,Li Y

    更新日期:2014-01-01 00:00:00

  • Spiracular air breathing in polypterid fishes and its implications for aerial respiration in stem tetrapods.

    abstract::The polypterids (bichirs and ropefish) are extant basal actinopterygian (ray-finned) fishes that breathe air and share similarities with extant lobe-finned sarcopterygians (lungfishes and tetrapods) in lung structure. They are also similar to some fossil sarcopterygians, including stem tetrapods, in having large paire...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4022

    authors: Graham JB,Wegner NC,Miller LA,Jew CJ,Lai NC,Berquist RM,Frank LR,Long JA

    更新日期:2014-01-01 00:00:00

  • Replication of flexible polymer membranes with geometry-controllable nano-apertures via a hierarchical mould-based dewetting.

    abstract::Membranes with nano-apertures are versatile templates that possess a wide range of electronic, optical and biomedical applications. However, such membranes have been limited to silicon-based inorganic materials to utilize standard semiconductor processes. Here we report a new type of flexible and free-standing polymer...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4137

    authors: Cho H,Kim J,Park H,Won Bang J,Seop Hyun M,Bae Y,Ha L,Yoon Kim D,Min Kang S,Jung Park T,Seo S,Choi M,Suh KY

    更新日期:2014-01-01 00:00:00

  • Actomyosin-dependent formation of the mechanosensitive talin-vinculin complex reinforces actin anchoring.

    abstract::The force generated by the actomyosin cytoskeleton controls focal adhesion dynamics during cell migration. This process is thought to involve the mechanical unfolding of talin to expose cryptic vinculin-binding sites. However, the ability of the actomyosin cytoskeleton to directly control the formation of a talin-vinc...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4095

    authors: Ciobanasu C,Faivre B,Le Clainche C

    更新日期:2014-01-01 00:00:00

  • Size-induced enhanced magnetoelectric effect and multiferroicity in chromium oxide nanoclusters.

    abstract::The control of the magnetization of a material with an electric field would make the design and the integration of novel electronic devices possible. This explains the renewed interest in multiferroic materials. Progress in this field is currently hampered by the scarcity of the materials available and the smallness o...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4167

    authors: Halley D,Najjari N,Majjad H,Joly L,Ohresser P,Scheurer F,Ulhaq-Bouillet C,Berciaud S,Doudin B,Henry Y

    更新日期:2014-01-01 00:00:00

  • Female monopolization mediates the relationship between pre- and postcopulatory sexual traits.

    abstract::Theory predicts a trade-off between investments in precopulatory (ornaments and armaments) and postcopulatory (testes and ejaculates) sexual traits due to the costs associated with their growth and maintenance within the finite energy resources available. Empirical studies, however, have revealed considerable inconsis...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4184

    authors: Lüpold S,Tomkins JL,Simmons LW,Fitzpatrick JL

    更新日期:2014-01-01 00:00:00

  • X-ray refinement significantly underestimates the level of microscopic heterogeneity in biomolecular crystals.

    abstract::Biomolecular X-ray structures typically provide a static, time- and ensemble-averaged view of molecular ensembles in crystals. In the absence of rigid-body motions and lattice defects, B-factors are thought to accurately reflect the structural heterogeneity of such ensembles. In order to study the effects of averaging...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4220

    authors: Kuzmanic A,Pannu NS,Zagrovic B

    更新日期:2014-01-01 00:00:00

  • Bending rules for animal propulsion.

    abstract::Animal propulsors such as wings and fins bend during motion and these bending patterns are believed to contribute to the high efficiency of animal movements compared with those of man-made designs. However, efforts to implement flexible designs have been met with contradictory performance results. Consequently, there ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4293

    authors: Lucas KN,Johnson N,Beaulieu WT,Cathcart E,Tirrell G,Colin SP,Gemmell BJ,Dabiri JO,Costello JH

    更新日期:2014-01-01 00:00:00

  • Long livestock farming history and human landscape shaping revealed by lake sediment DNA.

    abstract::The reconstruction of human-driven, Earth-shaping dynamics is important for understanding past human/environment interactions and for helping human societies that currently face global changes. However, it is often challenging to distinguish the effects of the climate from human activities on environmental changes. He...

    journal_title:Nature communications

    pub_type: 历史文章,杂志文章

    doi:10.1038/ncomms4211

    authors: Giguet-Covex C,Pansu J,Arnaud F,Rey PJ,Griggo C,Gielly L,Domaizon I,Coissac E,David F,Choler P,Poulenard J,Taberlet P

    更新日期:2014-01-01 00:00:00

  • Pod shattering resistance associated with domestication is mediated by a NAC gene in soybean.

    abstract::Loss of seed dispersal is a key agronomical trait targeted by ancient human selection and has been regarded as a milestone of crop domestication. In this study, in the legume crop soybean Glycine max (L.) Merr. which provides vegetable oils and proteins for humans, we show that the key cellular feature of the shatteri...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4352

    authors: Dong Y,Yang X,Liu J,Wang BH,Liu BL,Wang YZ

    更新日期:2014-01-01 00:00:00

  • Imprintable membranes from incomplete chiral coalescence.

    abstract::Coalescence is an essential phenomenon that governs the equilibrium behaviour in a variety of systems from intercellular transport to planetary formation. In this report, we study coalescence pathways of circularly shaped two-dimensional colloidal membranes, which are one rod-length-thick liquid-like monolayers of ali...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4063

    authors: Zakhary MJ,Gibaud T,Kaplan CN,Barry E,Oldenbourg R,Meyer RB,Dogic Z

    更新日期:2014-01-01 00:00:00

  • Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography.

    abstract::Lipidic cubic phase (LCP) crystallization has proven successful for high-resolution structure determination of challenging membrane proteins. Here we present a technique for extruding gel-like LCP with embedded membrane protein microcrystals, providing a continuously renewed source of material for serial femtosecond c...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4309

    authors: Weierstall U,James D,Wang C,White TA,Wang D,Liu W,Spence JC,Bruce Doak R,Nelson G,Fromme P,Fromme R,Grotjohann I,Kupitz C,Zatsepin NA,Liu H,Basu S,Wacker D,Han GW,Katritch V,Boutet S,Messerschmidt M,Williams GJ

    更新日期:2014-01-01 00:00:00

  • A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response.

    abstract::The Hippo pathway is an evolutionarily conserved regulator of organ size and tumorigenesis that negatively regulates cell growth and survival. Here we report that Yes-associated protein (YAP), the terminal effector of the Hippo pathway, interacts with FoxO1 in the nucleus of cardiomyocytes, thereby promoting survival....

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4315

    authors: Shao D,Zhai P,Del Re DP,Sciarretta S,Yabuta N,Nojima H,Lim DS,Pan D,Sadoshima J

    更新日期:2014-01-01 00:00:00

  • An asymmetric heterodomain interface stabilizes a response regulator-DNA complex.

    abstract::Two-component signal transduction systems consist of pairs of histidine kinases and response regulators, which mediate adaptive responses to environmental cues. Most activated response regulators regulate transcription by binding tightly to promoter DNA via a phosphorylation-triggered inactive-to-active transition. Th...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4282

    authors: Narayanan A,Kumar S,Evrard AN,Paul LN,Yernool DA

    更新日期:2014-01-01 00:00:00

  • Room-temperature sub-band gap optoelectronic response of hyperdoped silicon.

    abstract::Room-temperature infrared sub-band gap photoresponse in silicon is of interest for telecommunications, imaging and solid-state energy conversion. Attempts to induce infrared response in silicon largely centred on combining the modification of its electronic structure via controlled defect formation (for example, vacan...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4011

    authors: Mailoa JP,Akey AJ,Simmons CB,Hutchinson D,Mathews J,Sullivan JT,Recht D,Winkler MT,Williams JS,Warrender JM,Persans PD,Aziz MJ,Buonassisi T

    更新日期:2014-01-01 00:00:00

  • The central role of EED in the orchestration of polycomb group complexes.

    abstract::Polycomb repressive complexes 1 and 2 (PRC1 and 2) play a critical role in the epigenetic regulation of transcription during cellular differentiation, stem cell pluripotency and neoplastic progression. Here we show that the polycomb group protein EED, a core component of PRC2, physically interacts with and functions a...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4127

    authors: Cao Q,Wang X,Zhao M,Yang R,Malik R,Qiao Y,Poliakov A,Yocum AK,Li Y,Chen W,Cao X,Jiang X,Dahiya A,Harris C,Feng FY,Kalantry S,Qin ZS,Dhanasekaran SM,Chinnaiyan AM

    更新日期:2014-01-01 00:00:00

  • Direct chemical conversion of graphene to boron- and nitrogen- and carbon-containing atomic layers.

    abstract::Graphene and hexagonal boron nitride are typical conductor and insulator, respectively, while their hybrids hexagonal boron carbonitride are promising as a semiconductor. Here we demonstrate a direct chemical conversion reaction, which systematically converts the hexagonal carbon lattice of graphene to boron nitride, ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4193

    authors: Gong Y,Shi G,Zhang Z,Zhou W,Jung J,Gao W,Ma L,Yang Y,Yang S,You G,Vajtai R,Xu Q,MacDonald AH,Yakobson BI,Lou J,Liu Z,Ajayan PM

    更新日期:2014-01-01 00:00:00

  • Photonic Aharonov-Bohm effect in photon-phonon interactions.

    abstract::The Aharonov-Bohm effect is one of the most intriguing phenomena in both classical and quantum physics, and associates with a number of important and fundamental issues in quantum mechanics. The Aharonov-Bohm effects of charged particles have been experimentally demonstrated and found applications in various fields. R...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4225

    authors: Li E,Eggleton BJ,Fang K,Fan S

    更新日期:2014-01-01 00:00:00

  • TNF-α blockade induces IL-10 expression in human CD4+ T cells.

    abstract::IL-17+ CD4+ T (Th17) cells contribute to the pathogenesis of several human inflammatory diseases. Here we demonstrate that TNF inhibitor (TNFi) drugs induce the anti-inflammatory cytokine IL-10 in CD4+ T cells including IL-17+ CD4+ T cells. TNFi-mediated induction of IL-10 in IL-17+ CD4+ T cells is Treg-/Foxp3-indepen...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4199

    authors: Evans HG,Roostalu U,Walter GJ,Gullick NJ,Frederiksen KS,Roberts CA,Sumner J,Baeten DL,Gerwien JG,Cope AP,Geissmann F,Kirkham BW,Taams LS

    更新日期:2014-01-01 00:00:00

  • Polymorphism of dislocation core structures at the atomic scale.

    abstract::Dislocation defects together with their associated strain fields and segregated impurities are of considerable significance in many areas of materials science. However, their atomic-scale structures have remained extremely challenging to resolve, limiting our understanding of these ubiquitous defects. Here, by develop...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4239

    authors: Wang Z,Saito M,McKenna KP,Ikuhara Y

    更新日期:2014-01-01 00:00:00

  • Quantum metrology with parametric amplifier-based photon correlation interferometers.

    abstract::Conventional interferometers usually utilize beam splitters for wave splitting and recombination. These interferometers are widely used for precision measurement. Their sensitivity for phase measurement is limited by the shot noise, which can be suppressed with squeezed states of light. Here we study a new type of int...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4049

    authors: Hudelist F,Kong J,Liu C,Jing J,Ou ZY,Zhang W

    更新日期:2014-01-01 00:00:00

  • Dynamic urea bond for the design of reversible and self-healing polymers.

    abstract::Polymers bearing dynamic covalent bonds may exhibit dynamic properties, such as self-healing, shape memory and environmental adaptation. However, most dynamic covalent chemistries developed so far require either catalyst or change of environmental conditions to facilitate bond reversion and dynamic property change in ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4218

    authors: Ying H,Zhang Y,Cheng J

    更新日期:2014-01-01 00:00:00

  • The TORC1 effector kinase Npr1 fine tunes the inherent activity of the Mep2 ammonium transport protein.

    abstract::The TORC1 complex controls cell growth upon integrating nutritional signals including amino-acid availability. TORC1 notably adapts the plasma membrane protein content by regulating arrestin-mediated endocytosis of amino-acid transporters. Here we demonstrate that TORC1 further fine tunes the inherent activity of the ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4101

    authors: Boeckstaens M,Llinares E,Van Vooren P,Marini AM

    更新日期:2014-01-01 00:00:00

  • Critical roles of nardilysin in the maintenance of body temperature homoeostasis.

    abstract::Body temperature homoeostasis in mammals is governed centrally through the regulation of shivering and non-shivering thermogenesis and cutaneous vasomotion. Non-shivering thermogenesis in brown adipose tissue (BAT) is mediated by sympathetic activation, followed by PGC-1α induction, which drives UCP1. Here we identify...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4224

    authors: Hiraoka Y,Matsuoka T,Ohno M,Nakamura K,Saijo S,Matsumura S,Nishi K,Sakamoto J,Chen PM,Inoue K,Fushiki T,Kita T,Kimura T,Nishi E

    更新日期:2014-01-01 00:00:00

  • The locust genome provides insight into swarm formation and long-distance flight.

    abstract::Locusts are one of the world's most destructive agricultural pests and represent a useful model system in entomology. Here we present a draft 6.5 Gb genome sequence of Locusta migratoria, which is the largest animal genome sequenced so far. Our findings indicate that the large genome size of L. migratoria is likely to...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms3957

    authors: Wang X,Fang X,Yang P,Jiang X,Jiang F,Zhao D,Li B,Cui F,Wei J,Ma C,Wang Y,He J,Luo Y,Wang Z,Guo X,Guo W,Wang X,Zhang Y,Yang M,Hao S,Chen B,Ma Z,Yu D,Xiong Z,Zhu Y,Fan D,Han L,Wang B,Chen Y,Wang J

    更新日期:2014-01-01 00:00:00

  • African origin of the malaria parasite Plasmodium vivax.

    abstract::Plasmodium vivax is the leading cause of human malaria in Asia and Latin America but is absent from most of central Africa due to the near fixation of a mutation that inhibits the expression of its receptor, the Duffy antigen, on human erythrocytes. The emergence of this protective allele is not understood because P. ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4346

    authors: Liu W,Li Y,Shaw KS,Learn GH,Plenderleith LJ,Malenke JA,Sundararaman SA,Ramirez MA,Crystal PA,Smith AG,Bibollet-Ruche F,Ayouba A,Locatelli S,Esteban A,Mouacha F,Guichet E,Butel C,Ahuka-Mundeke S,Inogwabini BI,Ndjango

    更新日期:2014-01-01 00:00:00

  • Merging of metal nanoparticles driven by selective wettability of silver nanostructures.

    abstract::The welding and sintering of nanomaterials is relevant, for example, to form electrical contacts between metallic particles in printed electronic devices. Usually the welding of nanoparticles is achieved at high temperatures. Here we find that merging of two different metals, silver and gold nanoparticles, occurs on c...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms3994

    authors: Grouchko M,Roitman P,Zhu X,Popov I,Kamyshny A,Su H,Magdassi S

    更新日期:2014-01-01 00:00:00

  • Thermotropic phase boundaries in classic ferroelectrics.

    abstract::High-performance piezoelectrics are lead-based solid solutions that exhibit a so-called morphotropic phase boundary, which separates two competing phases as a function of chemical composition; as a consequence, an intermediate low-symmetry phase with a strong piezoelectric effect arises. In search for environmentally ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4172

    authors: Lummen TT,Gu Y,Wang J,Lei S,Xue F,Kumar A,Barnes AT,Barnes E,Denev S,Belianinov A,Holt M,Morozovska AN,Kalinin SV,Chen LQ,Gopalan V

    更新日期:2014-01-01 00:00:00

  • Familial Alzheimer's mutations within APPTM increase Aβ42 production by enhancing accessibility of ε-cleavage site.

    abstract::The high Aβ42/Aβ40 production ratio is a hallmark of familial Alzheimer's disease, which can be caused by mutations in the amyloid precursor protein (APP). The C-terminus of Aβ is generated by γ-secretase cleavage within the transmembrane domain of APP (APPTM), a process that is primed by an initial ε-cleavage at eith...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4037

    authors: Chen W,Gamache E,Rosenman DJ,Xie J,Lopez MM,Li YM,Wang C

    更新日期:2014-01-01 00:00:00

  • Casimir forces on a silicon micromechanical chip.

    abstract::Quantum fluctuations give rise to van der Waals and Casimir forces that dominate the interaction between electrically neutral objects at sub-micron separations. Under the trend of miniaturization, such quantum electrodynamical effects are expected to play an important role in micro- and nano-mechanical devices. Nevert...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms2842

    authors: Zou J,Marcet Z,Rodriguez AW,Reid MT,McCauley AP,Kravchenko II,Lu T,Bao Y,Johnson SG,Chan HB

    更新日期:2013-01-01 00:00:00

  • The Capsaspora genome reveals a complex unicellular prehistory of animals.

    abstract::To reconstruct the evolutionary origin of multicellular animals from their unicellular ancestors, the genome sequences of diverse unicellular relatives are essential. However, only the genome of the choanoflagellate Monosiga brevicollis has been reported to date. Here we completely sequence the genome of the filastere...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms3325

    authors: Suga H,Chen Z,de Mendoza A,Sebé-Pedrós A,Brown MW,Kramer E,Carr M,Kerner P,Vervoort M,Sánchez-Pons N,Torruella G,Derelle R,Manning G,Lang BF,Russ C,Haas BJ,Roger AJ,Nusbaum C,Ruiz-Trillo I

    更新日期:2013-01-01 00:00:00

  • Role of motor cortex NMDA receptors in learning-dependent synaptic plasticity of behaving mice.

    abstract::The primary motor cortex has an important role in the precise execution of learned motor responses. During motor learning, synaptic efficacy between sensory and primary motor cortical neurons is enhanced, possibly involving long-term potentiation and N-methyl-D-aspartate (NMDA)-specific glutamate receptor function. To...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms3258

    authors: Hasan MT,Hernández-González S,Dogbevia G,Treviño M,Bertocchi I,Gruart A,Delgado-García JM

    更新日期:2013-01-01 00:00:00

  • A plasma-treated chalcogenide switch device for stackable scalable 3D nanoscale memory.

    abstract::Stackable select devices such as the oxide p-n junction diode and the Schottky diode (one-way switch) have been proposed for non-volatile unipolar resistive switching devices; however, bidirectional select devices (or two-way switch) need to be developed for bipolar resistive switching devices. Here we report on a ful...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms3629

    authors: Lee MJ,Lee D,Cho SH,Hur JH,Lee SM,Seo DH,Kim DS,Yang MS,Lee S,Hwang E,Uddin MR,Kim H,Chung UI,Park Y,Yoo IK

    更新日期:2013-01-01 00:00:00

  • Selective isolation of gold facilitated by second-sphere coordination with α-cyclodextrin.

    abstract::Gold recovery using environmentally benign chemistry is imperative from an environmental perspective. Here we report the spontaneous assembly of a one-dimensional supramolecular complex with an extended {[K(OH₂)₆][AuBr₄](α-cyclodextrin)₂}n chain superstructure formed during the rapid co-precipitation of α-cyclodextrin...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms2891

    authors: Liu Z,Frasconi M,Lei J,Brown ZJ,Zhu Z,Cao D,Iehl J,Liu G,Fahrenbach AC,Botros YY,Farha OK,Hupp JT,Mirkin CA,Fraser Stoddart J

    更新日期:2013-01-01 00:00:00

  • Three-dimensional self-assembled photonic crystals with high temperature stability for thermal emission modification.

    abstract::Selective thermal emission in a useful range of energies from a material operating at high temperatures is required for effective solar thermophotovoltaic energy conversion. Three-dimensional metallic photonic crystals can exhibit spectral emissivity that is modified compared with the emissivity of unstructured metals...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms3630

    authors: Arpin KA,Losego MD,Cloud AN,Ning H,Mallek J,Sergeant NP,Zhu L,Yu Z,Kalanyan B,Parsons GN,Girolami GS,Abelson JR,Fan S,Braun PV

    更新日期:2013-01-01 00:00:00

  • Controlled formation and reflection of a bright solitary matter-wave.

    abstract::Bright solitons are non-dispersive wave solutions, arising in a diverse range of nonlinear, one-dimensional systems, including atomic Bose-Einstein condensates with attractive interactions. In reality, cold-atom experiments can only approach the idealized one-dimensional limit necessary for the realization of true sol...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms2893

    authors: Marchant AL,Billam TP,Wiles TP,Yu MM,Gardiner SA,Cornish SL

    更新日期:2013-01-01 00:00:00

  • Nitrogen-doped carbon nanomaterials as non-metal electrocatalysts for water oxidation.

    abstract::Efficient and low-cost electrocatalysts for the oxygen evolution reaction are essential components of renewable energy technologies, such as solar fuel synthesis and providing a hydrogen source for powering fuel cells. Here we report that the nitrogen-doped carbon materials function as the efficient oxygen evolution e...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms3390

    authors: Zhao Y,Nakamura R,Kamiya K,Nakanishi S,Hashimoto K

    更新日期:2013-01-01 00:00:00

  • From protein sequence to dynamics and disorder with DynaMine.

    abstract::Protein function and dynamics are closely related; however, accurate dynamics information is difficult to obtain. Here based on a carefully assembled data set derived from experimental data for proteins in solution, we quantify backbone dynamics properties on the amino-acid level and develop DynaMine--a fast, high-qua...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms3741

    authors: Cilia E,Pancsa R,Tompa P,Lenaerts T,Vranken WF

    更新日期:2013-01-01 00:00:00

  • Circadian rhythms in Mexican blind cavefish Astyanax mexicanus in the lab and in the field.

    abstract::Biological clocks have evolved as an adaptation to life on a rhythmic planet, synchronising physiological processes to the environmental light-dark cycle. Here we examine circadian clock function in Mexican blind cavefish Astyanax mexicanus and its surface counterpart. In the lab, adult surface fish show robust circad...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms3769

    authors: Beale A,Guibal C,Tamai TK,Klotz L,Cowen S,Peyric E,Reynoso VH,Yamamoto Y,Whitmore D

    更新日期:2013-01-01 00:00:00

  • A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates.

    abstract::Isolated populations can empower the identification of rare variation associated with complex traits through next generation association studies, but the generalizability of such findings remains unknown. Here we genotype 1,267 individuals from a Greek population isolate on the Illumina HumanExome Beadchip, in search ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms3872

    authors: Tachmazidou I,Dedoussis G,Southam L,Farmaki AE,Ritchie GR,Xifara DK,Matchan A,Hatzikotoulas K,Rayner NW,Chen Y,Pollin TI,O'Connell JR,Yerges-Armstrong LM,Kiagiadaki C,Panoutsopoulou K,Schwartzentruber J,Moutsianas L,UK1

    更新日期:2013-01-01 00:00:00

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